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They argue that the different phytochemicals present in many herbs will interact to enhance the therapeutic effects of the herb and dilute toxicity.Furthermore, they argue that a single ingredient may contribute to multiple effects.

Herbalists deny that herbal synergism can be duplicated with synthetic chemicals. ^]^[28]

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Phenolics contain phenol rings. The anthocyanins that give grapes their purple color, the isoflavones, the phytoestrogens from soy and the tannins that give tea its astringency are phenolics.

Turpenoids are built up from terpene building blocks. Each terpene consists of two paired isoprenes. The names monoterpenes, sesquiterpenes, diterpenes and triterpenes are based on the number of isoprene units. The fragrance of rose and lavender is due to monoterpenes.

Since herbalism is such a diverse field few generalizations apply universally. Nevertheless a rough consensus can be inferred.

Herbalists tend to use extracts from parts of plants, such as the roots or leaves but not isolate particular phytochemicals. Pharmaceutical medicine prefers single ingredients on the grounds that dosage can be more easily quantified. Herbalists reject the notion of a single active ingredient.

Pharmaceutical researchers recognize the concept of drug synergism but note that clinical trials may be used to investigate the efficacy of a particular herbal preparation, provided the formulation of that herb is consistent.They argue that phytochemical interactions and trace components may alter the drug response in ways that cannot currently be replicated with a combination of a few putative active ingredients.

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